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KMID : 0361020220650070414
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Korean Journal of Otolaryngology - Head and Neck Surgery
2022 Volume.65 No. 7 p.414 ~ p.418
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A Case of Laryngeal Amyloidosis: Role of US and US-CNB for Preoperative Diagnosis
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Ahn Dong-Bin
Oh Eun-Jung
Kwak Ji-Hye
Sohn Jin-Ho
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Abstract
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Amyloidosis is a rare benign disease characterized by the extracellular deposition of nonsolublefibrillar proteins (amyloids) within organs. Laryngeal amyloidosis (LA) accounts for only9%-15% of all cases of amyloidosis. Since clinical manifestations and laryngoscopic findingsoften overlap with those of laryngeal cancer, it is challenging to differentiate LA from laryngealcancer prior to surgical biopsy. We report a case of LA mimicking laryngeal cancer, inwhich the diagnosis was facilitated by preoperative ultrasonography (US) and US-guidedcore-needle biopsy (US-CNB) prior to surgical biopsy. The US findings of this case were distinguishablefrom those of laryngeal cancer, which enabled us to consider a diagnosis otherthan laryngeal cancer. Amyloidosis was diagnosed preoperatively using office-based percutaneousUS-CNB, avoiding general anesthesia needed for suspension laryngoscopic examination.
This case suggests that US and US-CNB could be used as supplementary diagnostic modalitiesto evaluate suspicious laryngeal masses mimicking laryngeal cancer.
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KEYWORD
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Amyloidosis, Image-guided biopsy, Laryngeal neoplasm, Larynx, Ultrasonography
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